Overview of Adverse Events
(Safety Set)
Population
Placebo
Xanomeline
High Dose
Xanomeline
Low Dose
Total
Adverse Event
301 (100%)
435 (100%)
455 (100%)
1191 (100%)
Serious Event
NA
1 (0.2%)
2 (0.4%)
3 (0.3%)
Involves Cancer
NA
3 (0.7%)
1 (0.2%)
4 (0.3%)
Persist or Signif
Disability/Incapacity
NA
1 (0.2%)
NA
1 (0.1%)
Reults in Death
2 (0.7%)
1 (0.2%)
NA
3 (0.3%)
Requires or Prolongs
Hospitalization
12 (4%)
11 (2.5%)
9 (2%)
32 (2.7%)
Is Life Threatening
4 (1.3%)
1 (0.2%)
1 (0.2%)
6 (0.5%)
NOTE: N in column headers represents number of subjects entered in study (i.e., signed informed consent).
